LOBULAR BREAST CANCER IN SITU (LCIS)

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Written by : Dr.M.D.Mazumdar, MD

Lobular Carcinoma In Situ (LCIS) is a type of breast cancer which starts in the cells of a part of the breast known as the 'lobules'.

Each breast has about 20 lobules which are drained by ducts which carry the milk to the nipples.

LCIS develops in these lobules but does not break through the basement membrane to spread to the surrounding tissue.

'In situ' is a Latin word meaning 'in place'. It is also referred to as TIS, which means 'tumor in situ' or 'in the same place'.

LCIS is often referred to as a precancerous condition. About 25% of women with LCIS will develop breast cancer over time.

Lobular breast cancer is the second most common type of breast cancer. It is less common than ductal breast cancer and more common than other types of breast cancers like Inflammatory Breast cancer and Paget's Disease of the Breast .

LOBULAR CARCINOMA IN SITU

Age

LCIS commonly occurs at around the the ages of 40 and 50 years. It is more common before menopause has occured and is extremely rare in men.

Symptoms of Lobular Breast Cancer (LCIS):

No Symptoms: In most cases, LCIS produces no symptoms of breast cancer at all. It may be diagnosed only after biopsy of a suspicious lump seen at routine mammography or physical examination. LCIS frequently does not show up in a mammography.
Breast Lump: In some cases, a small lump may be felt in a part of the breast. But again, it is only after a biopsy that LCIS can be definitely diagnosed. Like most breast cancers, these are also non-tender and firm lumps.
Nipple Discharge: LCIS rarely produces nipple diischarge.
Pain: Pain is very uncommon. But in the presence of infection of the lumpo, there may be some amount of pain.

Stages of LCIS:

LCIS is generally considered to be Stage O of Ductal breast cancer since it is non-invasive. The breast cancer staging system is used to describe how far cancer has spread beyond the site of the original tumor. Both LCIS and DCIS are considered Stage 0, the earliest stage possible.

See Page 2 for:

Diagnosis of LCIS

Treatment of LCIS

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LOBULAR BREAST CANCER IN SITU (LCIS)

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